Genetics Links:

The Reproductive Genomics Program at the Jackson Laboratory is funded by a Program Project grant from the Institute of Child Health and Human Development PO1 HD42137. It is a collaborative effort among the laboratories of John Eppig, Mary Ann Handel, and John Schimenti. The goal is to use random chemical mutagenesis of the genome to produce mouse models of infertility. At least 800 families of mice will be screened for infertility mutations over the next 4 years in a strategy that will produce over 100 mutant models.
A major goal is to make this collection of mutants a valuable and practical resource for the community of Developmental and Reproductive Biologists. This will be accomplished by performing a basic phenotype characterization of each mutant to classify the nature of the defect, and genetically mapping as many mutations as possible to facilitate stock maintenance and aid positional cloning.

TBASE is "an attempt to organize information on transgenic animals and targeted mutations generated and analyzed worldwide". It has a searchable databases for mutants and literature, an events calandar, a glossary, and links page.

The Knockouts database. Primarily concerned with nervous system phenotypes, you can search this database for "knockout" literature based on knockout type, author, title or publication.

BioMedNet: This is a general purpose biological/medical website. They have different sections for News & Comment, Research Tools, Books and Labware, Web Links, Journal Collection, Reviews, and Jobs. They also claim to have more than 730,000 members.

Germonline GermOnline is a gateway for gametogenesis. Its goals are to provide a rapid access to a comprehensive compilation of genes, expression data and functions implicated in germline development, meiosis, gamete formation, and gamete function in 11 key model systems and H. sapiens.

Molecular and Genomic Toxicology Laboratory. This site's focus is on Endocrine Disruption and Toxicogenomics; in addition, they have a database called dbTEST which is intended to encompass all genes known to be expressed in the testis.

The Ovarian Kaleidoscope Database. This site focuses on " information regarding the biological function, expression pattern and regulation of genes expressed in the ovary". It has a searchable database and educational information.

The I.M.A.G.E. Consortium The I.M.A.G.E. Consortium "shares high-quality, arrayed cDNA libraries and places sequence, map, and expression data on the clones in these arrays into the public domain". If you need human or mouse cDNA, these are good people to talk to. (More species coming).

National Center for Biotechnology Information: N.C.B.I. From their home page: "Established in 1988 as a national resource for molecular biology information, NCBI creates public databases, conducts research in computational biology, develops software tools for analyzing genome data, and disseminates biomedical information - all for the better understanding of molecular processes affecting human health and disease.".
This is a huge and popular website containing literature, Nucleotide, and Protein databases. They also operate a BLAST site for finding orthologs, a taxonomy database, and 3D structure information for many proteins. A partial list of information found on this site includes:

Jackson Labs The Jackson Labs focus primarily on human and mouse genetics. They support research, have a searchable database, supply mutant strains of mice to other labs, and are an educational institution.

Wormbase Wormbase is an exaustive database focused on C elegans, a tiny nematode (worm) extensively used in studies of genetics. Wormbase is home to the authors of AceDB, which is database software specificly designed to store genetic information and is used as the basis of many other databases for other organisms.

UniGene "UniGene is an experimental system for automatically partitioning GenBank sequences into a non-redundant set of gene-oriented clusters". It is operated by the N.C.B.I. and incorportes both well-characterized genes and EST sequences, essentially a wherehouse of sequence information.

Saccharomyces Genome Database
Very complete site on the yeast Sacchraromyces. Includes searchable databases, sequence and analysis tools, maps, literature guides, downloadable data, community information, and links to other yeast sites.

Biology of Reproduction
Biology of Reproduction is the official journal of the Society for the Study of Reproduction (SSR) and publishes original research on a broad range of topics in the field of reproductive biology, as well as minireviews on topics of current importance or controversy.

Flybase
A Database of the Drosophila Genome; very comprehensive site providing for all you fly-based needs.

The Androgen Receptor Gene Mutations Database
A database/website "for all who are interested in mutations of the Androgen Receptor Gene".

Green Center for Reproductive Biology Sciences From their mission statement: "provide a link between the mechanisms of gamete development, the molecular basis of fertilization, and the bases of maintenance and acquisition of cellular totipotency or pluripotency".


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